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doi: 10.3389/fcell.2022.964130 61

Concomitant use of ENDOCET with a CYP3A4 inhibitor, such as macrolide antibiotics (e.g., erythromycin), azole-antifungal agents (e.g., ketoconazole), and protease inhibitors (e.g., ritonavir), may increase plasma concentrations of oxycodone hydrochloride and prolong opioid adverse reactions, which may cause potentially fatal respiratory depression [see WARNINGS], particularly when an inhibitor is added after a stable dose of ENDOCET is achieved

Gentle exercise like walking improves circulation and may reduce headache severity

The pigment compositions of leaves changed under low temperatures in various plants 20